Septerna Inc $SEPN

Health Care

$40.88
+0.12 (+0.29%)
As of Oct 22, 2026, 9:33 PM EDT · cached
Price history
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Septerna Inc (SEPN) is trading up at $40.88 (+0.29%), as of the latest quote. It is a Russell 2000 constituent in the Health Care sector.

IPO: October 25, 2024 · $18.00 offering · NASDAQ · View IPO details →

Septerna Inc revenue & net income history (FY2023–FY2025)

RevenueNet incomeNet margin (right axis, %)
$46.0M−$12.9M−$71.8MFY2023 revenue: $151.0KFY2023 net income: $4.18M · Net margin 2768.2%'23FY2024 revenue: $1.07MFY2024 net income: −$71.8M · Net margin −6678.9%'24FY2025 revenue: $46.0MFY2025 net income: −$48.9M · Net margin −106.4%'25−4000%−2000%0%2000%FY2023 net margin: 2768.2%FY2024 net margin: −6678.9% (off the scale, which stops at −4325.3%)FY2025 net margin: −106.4%
Septerna Inc annual financial statements
FY2023Dec 2023FY2024Dec 2024FY2025Dec 2025
Income statement
Revenue$151.0K$1.07M$46.0M
Growth (year over year)—+611.9%+4174.5%
Operating income$2.08M−$80.8M−$68.3M
Operating margin1374.2%−7518.4%−148.6%
Net income$4.18M−$71.8M−$48.9M
Net margin2768.2%−6678.9%−106.4%
EPS (diluted)$0.29−$7.26−$1.10
Balance sheet
Cash and equivalents$88.5M$238.2M$120.7M
Total assets$130.9M$456.6M$596.2M
Total liabilities$20.0M$36.5M$214.3M
Shareholders' equity−$38.4M$420.0M$381.9M
Cash flow
Operating cash flow−$38.7M−$67.5M$110.2M
Capital expenditure$2.88M$2.10M$518.0K
Free cash flow−$41.6M−$69.6M$109.7M

From Septerna Inc's 10-K and 10-Q filings with the SEC; its fiscal year ends in December. Each period shows the latest figure the company has reported for it, including restatements. Net margin is our own calculation from those reported figures (net income ÷ revenue); it is left blank where revenue is zero or missing. † Quarter derived from the company's year-to-date or full-year totals. Filings on SEC EDGAR →

About Septerna Inc

Headquarters
South San Francisco, California From SEC filings, Oct 2026

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