Lexicon Pharmaceuticals $LXRX

Health Care

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Lexicon Pharmaceuticals (LXRX) is a Health Care company in the Russell 2000. Latest news and coverage below.

Lexicon Pharmaceuticals revenue & net income history (FY2016–FY2025)

RevenueNet income
$322.1M$60.8M−$200.4MFY2016 revenue: $79.3MFY2016 net income: −$131.4M'16FY2017 revenue: $91.7MFY2017 net income: −$123.0M'17FY2018 revenue: $63.2MFY2018 net income: −$120.5M'18FY2019 revenue: $322.1MFY2019 net income: $130.1M'19FY2020 revenue: $24.0MFY2020 net income: −$58.6M'20FY2021 revenue: $298.0KFY2021 net income: −$87.8M'21FY2022 revenue: $139.0KFY2022 net income: −$101.9M'22FY2023 revenue: $1.20MFY2023 net income: −$177.1M'23FY2024 revenue: $31.1MFY2024 net income: −$200.4M'24FY2025 revenue: $49.8MFY2025 net income: −$50.3M'25
Lexicon Pharmaceuticals annual financial statements
FY2016Dec 2016FY2017Dec 2017FY2018Dec 2018FY2019Dec 2019FY2020Dec 2020FY2021Dec 2021FY2022Dec 2022FY2023Dec 2023FY2024Dec 2024FY2025Dec 2025
Income statement
Revenue$79.3M$91.7M$63.2M$322.1M$24.0M$298.0K$139.0K$1.20M$31.1M$49.8M
Growth (year over year)−39.0%+15.7%−31.1%+409.5%−92.5%−98.8%−53.4%+766.2%+2481.5%+60.2%
Gross profit$79.3M$89.8M$60.7M$318.8M$22.1M$298.0K$139.0K$1.12M$30.5M$49.5M
Gross margin100.0%97.9%96.1%99.0%92.0%100.0%100.0%92.9%98.0%99.4%
Operating income−$127.2M−$130.6M−$103.3M$141.4M−$47.8M−$87.1M−$100.8M−$171.8M−$197.1M−$48.9M
Operating margin−160.5%−142.5%−163.4%43.9%−199.2%−29224.8%−72489.2%−14265.0%−634.2%−98.2%
Net income−$131.4M−$123.0M−$120.5M$130.1M−$58.6M−$87.8M−$101.9M−$177.1M−$200.4M−$50.3M
Net margin−165.8%−134.1%−190.7%40.4%−244.1%−29449.0%−73341.0%−14710.9%−644.8%−101.1%
EPS (diluted)−$1.27−$1.17−$1.14$1.16−$0.53−$0.60−$0.62−$0.80−$0.63−$0.14
Balance sheet
Cash and equivalents$46.6M$61.7M$80.4M$36.1M$126.3M$64.1M$46.3M$22.5M$66.7M$34.3M
Total assets$475.6M$436.5M$284.1M$417.7M$203.8M$136.9M$194.3M$229.4M$298.4M$185.0M
Total liabilities$318.2M$368.3M$310.5M$300.6M$47.4M$23.3M$77.2M$136.3M$152.5M$77.4M
Long-term debt$85.2M$231.6M$243.9M$234.2M$0$0$48.6M$99.5M$100.3M$49.4M
Shareholders' equity$167.5M$68.3M−$26.4M$117.1M$156.4M$113.6M$117.1M$93.1M$145.9M$107.5M
Cash flow
Operating cash flow−$175.6M−$185.4M−$148.6M$113.8M−$143.0M−$87.0M−$88.9M−$161.9M−$178.8M−$67.9M
Capital expenditure$231.0K$228.0K$95.0K$70.0K$87.0K$1.22M$1.33M$470.0K$1.03M$0
Free cash flow−$175.9M−$185.6M−$148.7M$113.7M−$143.1M−$88.2M−$90.2M−$162.4M−$179.8M−$67.9M
Share buybacks$621.0K$1.68M$972.0K$941.0K$1.03M$2.67M$864.0K$824.0K$1.73M—

From Lexicon Pharmaceuticals's 10-K and 10-Q filings with the SEC; its fiscal year ends in December. Each period shows the latest figure the company has reported for it, including restatements. † Quarter derived from the company's year-to-date or full-year totals. Filings on SEC EDGAR →

About Lexicon Pharmaceuticals

Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company developing treatments for human disease. The company was founded in 1995 in The Woodlands, Texas under the name Lexicon Genetics, Incorporated by co-founders Professor Allan Bradley, FRS and Professor Bradley's postdoctoral fellow Arthur T Sands. The company has used its mouse gene knockout technology and in vivo screening capabilities to study nearly 5,000 genes in its Genome5000 program and has identified over 100 potential therapeutic targets. Lexicon has advanced multiple drug candidates into human clinical trials and has a broad and diverse pipeline of drug targets behind its clinical programs. Lexicon is pursuing drug targets in five therapeutic areas including oncology, gastroenterology, immunology, metabolism, and ophthalmology.

Source: Wikipedia — Lexicon Pharmaceuticals

Headquarters
The Woodlands, Texas From SEC filings, Oct 2026

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