Karyopharm Therapeutics $KPTI

Health Care

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Karyopharm Therapeutics (KPTI) is a Health Care company in the Russell 2000. Latest news and coverage below.

Karyopharm Therapeutics revenue & net income history (FY2016–FY2025)

RevenueNet income
$209.8M$5.11M−$199.6MFY2016 revenue: $154.0KFY2016 net income: −$109.6M'16FY2017 revenue: $1.60MFY2017 net income: −$129.0M'17FY2018 revenue: $30.3MFY2018 net income: −$178.4M'18FY2019 revenue: $40.9MFY2019 net income: −$199.6M'19FY2020 revenue: $108.1MFY2020 net income: −$196.3M'20FY2021 revenue: $209.8MFY2021 net income: −$124.1M'21FY2022 revenue: $157.1MFY2022 net income: −$165.3M'22FY2023 revenue: $146.0MFY2023 net income: −$143.1M'23FY2024 revenue: $145.2MFY2024 net income: −$76.4M'24FY2025 revenue: $146.1MFY2025 net income: −$196.0M'25
Karyopharm Therapeutics annual financial statements
FY2016Dec 2016FY2017Dec 2017FY2018Dec 2018FY2019Dec 2019FY2020Dec 2020FY2021Dec 2021FY2022Dec 2022FY2023Dec 2023FY2024Dec 2024FY2025Dec 2025
Income statement
Revenue$154.0K$1.60M$30.3M$40.9M$108.1M$209.8M$157.1M$146.0M$145.2M$146.1M
Growth (year over year)−38.4%+942.2%+1790.1%+34.8%+164.3%+94.1%−25.1%−7.0%−0.5%+0.6%
Operating income−$110.7M−$130.5M−$179.9M−$189.3M−$171.8M−$98.3M−$142.2M−$129.5M−$119.4M−$90.7M
Operating margin−71903.9%−8133.2%−593.0%−462.9%−159.0%−46.8%−90.5%−88.7%−82.2%−62.1%
Net income−$109.6M−$129.0M−$178.4M−$199.6M−$196.3M−$124.1M−$165.3M−$143.1M−$76.4M−$196.0M
Net margin−71153.9%−8036.4%−588.1%−488.1%−181.6%−59.1%−105.2%−98.0%−52.6%−134.2%
EPS (diluted)−$657.00−$632.25−$706.50−$724.50−$40.80−$24.75−$30.30−$18.79−$14.00−$17.93
Balance sheet
Cash and equivalents$49.7M$69.0M$118.0M$128.9M$85.9M$190.5M$135.2M$52.2M$62.5M$60.5M
Total assets$180.4M$180.3M$341.2M$295.0M$313.1M$305.3M$358.2M$240.4M$164.4M$108.4M
Total liabilities$18.1M$50.8M$158.0M$245.2M$262.5M$385.0M$374.8M$376.6M$350.4M$401.3M
Long-term debt—————$169.3M————
Shareholders' equity$162.2M$129.5M$183.2M$49.8M$50.5M−$79.7M−$16.7M−$136.2M−$186.0M−$292.9M
Cash flow
Operating cash flow−$84.4M−$73.7M−$159.1M−$190.8M−$160.2M−$107.1M−$149.6M−$92.7M−$127.5M−$75.4M
Capital expenditure$70.0K$62.0K$2.36M$206.0K$145.0K$212.0K$118.0K$0$142.0K$0
Free cash flow−$84.5M−$73.8M−$161.5M−$191.0M−$160.4M−$107.3M−$149.7M−$92.7M−$127.6M−$75.4M

From Karyopharm Therapeutics's 10-K and 10-Q filings with the SEC; its fiscal year ends in December. Each period shows the latest figure the company has reported for it, including restatements. † Quarter derived from the company's year-to-date or full-year totals. Filings on SEC EDGAR →

About Karyopharm Therapeutics

Headquarters
Newton, Massachusetts From SEC filings, Oct 2026

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